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[title] => Mathematical modeling suggests U.S. counties are still unprepared for COVID spikes
[link] => https://coolnspicy.com/healthandscience/mathematical-modeling-suggests-u-s-counties-are-still-unprepared-for-covid-spikes/
[dc] => Array
(
[creator] => Tony Grantly
)
[pubdate] => Mon, 31 Oct 2022 11:37:12 +0000
[category] => Health And SciencecountiesCovidMathematicalmodelingspikessuggestsunprepared
[guid] => https://coolnspicy.com/?p=55875
[description] => Journal Reference: Joel E. Cohen, Richard A. Davis, Gennady Samorodnitsky. COVID-19 cases and deaths in the United States follow Taylor’s law for heavy-tailed distributions with infinite variance. Proceedings of the National Academy of Sciences, 2022; 119 (38) DOI: 10.1073/pnas.2209234119 The study tests a model that closely matches the patterns of case counts and deaths reported, ... Read more
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[encoded] =>
Journal Reference:
Joel E. Cohen, Richard A. Davis, Gennady Samorodnitsky. COVID-19 cases and deaths in the United States follow Taylor’s law for heavy-tailed distributions with infinite variance. Proceedings of the National Academy of Sciences, 2022; 119 (38) DOI: 10.1073/pnas.2209234119
The study tests a model that closely matches the patterns of case counts and deaths reported, county by county, across the United States between April 2020 and June 2021. The model suggests that unprecedented COVID spikes could, even now, overwhelm local jurisdictions.
“Our best estimate, based on the data, is that the numbers of cases and deaths per county have infinite variance, which means that a county could get hit with a tremendous number of cases or deaths,” says Rockefeller’s Joel Cohen. “We cannot reasonably anticipate that any county will have the resources to cope with extremely large, rare events, so it is crucial that counties — as well as states and even countries — develop plans, ahead of time, to share resources.”
Predicting 99 percent of a pandemic
Ecologists might have guessed that the spread of COVID cases and deaths would at least roughly conform to Taylor’s Law, a formula that relates a population’s mean to its variance (a measure of the scatter around the average). From how crop yields fluctuate, to the frequency of tornado outbreaks, to how cancer cells multiply, Taylor’s Law forms the backbone of many statistical models that experts use to describe thousands of species, including humans.
But when Cohen began looking into whether Taylor’s Law could also describe the grim COVID statistics provided by The New York Times, he ran into a surprise.
Ninety-nine percent of counties’ counts of cases and deaths between April 2020 and June 2021 conformed to a “lognormal” distribution of Taylor’s Law, which predicts that the variance of cases or deaths in each location will be proportional to the squared mean of cases or deaths. For example, if the average number of cases per county is 50 in Arizona and 100 in California, this version of Taylor’s Law would predict that the scatter of case counts in California would be four times larger than the scatter of case counts in Arizona. Similarly, if the case counts per county in those two states were 50 and 150, respectively, the scatter would be nine times larger in California.
The top one percent of counts of cases and deaths, however, did not fit the lognormal distribution. Instead, the high counts matched the Pareto distribution — a model more often seen in economics than biology, in which extremely high values are rarely but regularly observed (think: income or wealth distribution). What made this particular Pareto distribution unique was that it also had infinite variance, implying that the scatter would increase beyond any finite limit, the more counts of cases or deaths observed. The challenge was to understand why even the top 1% of counts still conformed to Taylor’s Law with the same exponent as the lower 99%.
“It was a puzzle,” Cohen recalls. “And I sat on that puzzle, every so often taking it out, torturing it a bit, and putting it away. Until, one day, I called in the heavy artillery.”
The remaining one percent
Cohen sent his computer simulations and unproved conjectures to Richard A. Davis of Columbia University and Gennady Samorodnitsky of Cornell University, asking for their input. A few months later, the two sent him some theorems: the missing proof that Taylor’s Law would hold even for the Pareto-distributed top 1% of counties, with the same exponent as the 99% of lognormally distributed counties. “These theorems helped prove that Taylor’s Law accurately describes all of the data,” Cohen says. “The pandemic produced an orderly pattern of counts of cases per county and deaths per county. The unexpected part of that order was that, in the most extreme cases, there was no limit to how bad things could get.”
Infinite variance, near-infinite trouble
Why the pandemic follows this hybrid (lognormal-Pareto) version of Taylor’s Law so closely is unclear. One possibility is that Taylor’s Law — which describes the variance of many ecological systems, including infectious diseases like measles and Chagas’s disease — simply captures the nature of infection. If one patient infects two people (with some probability) and each of those two patients infect another two people (with some probability), we would expect cases to increase exponentially (with some probability), and occasional random events could cause infinite variance.
Cohen hopes that the study will sound an alarm for policymakers. An infinite variance of cases and deaths per county means that there is a very unlikely but possible scenario in which a COVID spike gets every individual in that county sick, or worse. Although the advent of vaccines makes such a scenario increasingly unlikely, areas in the United States and abroad with low vaccination rates still face the possibility of spikes that they cannot handle.
The math, Cohen says, suggests that COVID cases and deaths could far exceed the capacity of local jurisdictions to cope. “Governments had better be prepared to call in their friends,” he says.
We want to thank the writer of this write-up for this remarkable material
)
[summary] => Journal Reference: Joel E. Cohen, Richard A. Davis, Gennady Samorodnitsky. COVID-19 cases and deaths in the United States follow Taylor’s law for heavy-tailed distributions with infinite variance. Proceedings of the National Academy of Sciences, 2022; 119 (38) DOI: 10.1073/pnas.2209234119 The study tests a model that closely matches the patterns of case counts and deaths reported, ... Read more
[atom_content] =>
Journal Reference:
Joel E. Cohen, Richard A. Davis, Gennady Samorodnitsky. COVID-19 cases and deaths in the United States follow Taylor’s law for heavy-tailed distributions with infinite variance. Proceedings of the National Academy of Sciences, 2022; 119 (38) DOI: 10.1073/pnas.2209234119
The study tests a model that closely matches the patterns of case counts and deaths reported, county by county, across the United States between April 2020 and June 2021. The model suggests that unprecedented COVID spikes could, even now, overwhelm local jurisdictions.
“Our best estimate, based on the data, is that the numbers of cases and deaths per county have infinite variance, which means that a county could get hit with a tremendous number of cases or deaths,” says Rockefeller’s Joel Cohen. “We cannot reasonably anticipate that any county will have the resources to cope with extremely large, rare events, so it is crucial that counties — as well as states and even countries — develop plans, ahead of time, to share resources.”
Predicting 99 percent of a pandemic
Ecologists might have guessed that the spread of COVID cases and deaths would at least roughly conform to Taylor’s Law, a formula that relates a population’s mean to its variance (a measure of the scatter around the average). From how crop yields fluctuate, to the frequency of tornado outbreaks, to how cancer cells multiply, Taylor’s Law forms the backbone of many statistical models that experts use to describe thousands of species, including humans.
But when Cohen began looking into whether Taylor’s Law could also describe the grim COVID statistics provided by The New York Times, he ran into a surprise.
Ninety-nine percent of counties’ counts of cases and deaths between April 2020 and June 2021 conformed to a “lognormal” distribution of Taylor’s Law, which predicts that the variance of cases or deaths in each location will be proportional to the squared mean of cases or deaths. For example, if the average number of cases per county is 50 in Arizona and 100 in California, this version of Taylor’s Law would predict that the scatter of case counts in California would be four times larger than the scatter of case counts in Arizona. Similarly, if the case counts per county in those two states were 50 and 150, respectively, the scatter would be nine times larger in California.
The top one percent of counts of cases and deaths, however, did not fit the lognormal distribution. Instead, the high counts matched the Pareto distribution — a model more often seen in economics than biology, in which extremely high values are rarely but regularly observed (think: income or wealth distribution). What made this particular Pareto distribution unique was that it also had infinite variance, implying that the scatter would increase beyond any finite limit, the more counts of cases or deaths observed. The challenge was to understand why even the top 1% of counts still conformed to Taylor’s Law with the same exponent as the lower 99%.
“It was a puzzle,” Cohen recalls. “And I sat on that puzzle, every so often taking it out, torturing it a bit, and putting it away. Until, one day, I called in the heavy artillery.”
The remaining one percent
Cohen sent his computer simulations and unproved conjectures to Richard A. Davis of Columbia University and Gennady Samorodnitsky of Cornell University, asking for their input. A few months later, the two sent him some theorems: the missing proof that Taylor’s Law would hold even for the Pareto-distributed top 1% of counties, with the same exponent as the 99% of lognormally distributed counties. “These theorems helped prove that Taylor’s Law accurately describes all of the data,” Cohen says. “The pandemic produced an orderly pattern of counts of cases per county and deaths per county. The unexpected part of that order was that, in the most extreme cases, there was no limit to how bad things could get.”
Infinite variance, near-infinite trouble
Why the pandemic follows this hybrid (lognormal-Pareto) version of Taylor’s Law so closely is unclear. One possibility is that Taylor’s Law — which describes the variance of many ecological systems, including infectious diseases like measles and Chagas’s disease — simply captures the nature of infection. If one patient infects two people (with some probability) and each of those two patients infect another two people (with some probability), we would expect cases to increase exponentially (with some probability), and occasional random events could cause infinite variance.
Cohen hopes that the study will sound an alarm for policymakers. An infinite variance of cases and deaths per county means that there is a very unlikely but possible scenario in which a COVID spike gets every individual in that county sick, or worse. Although the advent of vaccines makes such a scenario increasingly unlikely, areas in the United States and abroad with low vaccination rates still face the possibility of spikes that they cannot handle.
The math, Cohen says, suggests that COVID cases and deaths could far exceed the capacity of local jurisdictions to cope. “Governments had better be prepared to call in their friends,” he says.
We want to thank the writer of this write-up for this remarkable material
)
[1] => Array
(
[title] => Napoli is a steamroller: 3-0 to Rangers, now at Anfield to fight for the first place
[link] => https://coolnspicy.com/sport/napoli-is-a-steamroller-3-0-to-rangers-now-at-anfield-to-fight-for-the-first-place/
[dc] => Array
(
[creator] => Tim Hall
)
[pubdate] => Mon, 31 Oct 2022 10:49:47 +0000
[category] => SportAnfieldfightNapoliRangerssteamroller
[guid] => https://coolnspicy.com/?p=55869
[description] =>
The streak of success gets longer. The Napoli is a steamroller, continues to grind the game and bring home victories in Italy and Europe. Rangers also fall under the pounding game of Spalletti’s team on the penultimate day of the Champions League group. With the 3-0 at Maradona, the Azzurri maintain ... Read more
[content] => Array
(
[encoded] =>
The streak of success gets longer. The Napoli is a steamroller, continues to grind the game and bring home victories in Italy and Europe. Rangers also fall under the pounding game of Spalletti’s team on the penultimate day of the Champions League group. With the 3-0 at Maradona, the Azzurri maintain a full score and reach the twelfth consecutive victory between league and cup, an absolute record that speaks volumes about the magical moment that the team is experiencing.
To complete the party, after the qualification for the round of 16 already materialized on the previous day with the victory over Ajax, only the mathematical conquest of the first place in the group is missing because the victory of Liverpool in Amsterdam postpones the final verdict to the direct match in the program. on the last day Tuesday of next week at Anfield. For Napoli it will be enough not to be defeated by Liverpool with more than three goals to qualify for first place and to be able to hope for a more favorable draw.
The game with Rangers has practically no history. Despite Spalletti initially leaving important players such as Osimhen, Kvaratskhelia, Lozano, Zielinski, Anguissa and Juan Jesus on the bench, the technical-tactical differences with the Scots turn out to be enormous. Napoli leads the game at will and after a quarter of an hour from the start of the match they are already ahead by two goals, thanks to a brace from Simeone, who bags at 10 ‘with a diagonal from the right and at 15’ with a diving header. The game mechanics of Spalletti’s team remain unchanged despite the numerous changes compared to the basic line-up.
The maneuver is always fluid and ball possession is suffocating for the opponents. The Rangers are constantly attacked when they are preparing to start the maneuver and fail to propose offensive maneuvers that can put the rearguard of the hosts in difficulty. In the second half, Napoli pays more attention to administering the advantage without wasting too much energy and the Scots face in some circumstances in the penalty area but fail to create problems for Meret.
Spalletti makes all the substitutions he has available and also gives a presence in the Champions League to some young players of the squad such as Gaetano, Zerbin and Zanoli. The Azzurri scored the third goal ten minutes from the end of the match. On the cross from the flag of Raspadori stands Ostigard in the penalty area who hits his head and sends the ball into the net. It ends with yet another success. In Liverpool the last act of the first phase of the Champions League will take place in which Napoli is proceeding in forced marches and as a true dominator.
)
[summary] =>
The streak of success gets longer. The Napoli is a steamroller, continues to grind the game and bring home victories in Italy and Europe. Rangers also fall under the pounding game of Spalletti’s team on the penultimate day of the Champions League group. With the 3-0 at Maradona, the Azzurri maintain ... Read more
[atom_content] =>
The streak of success gets longer. The Napoli is a steamroller, continues to grind the game and bring home victories in Italy and Europe. Rangers also fall under the pounding game of Spalletti’s team on the penultimate day of the Champions League group. With the 3-0 at Maradona, the Azzurri maintain a full score and reach the twelfth consecutive victory between league and cup, an absolute record that speaks volumes about the magical moment that the team is experiencing.
To complete the party, after the qualification for the round of 16 already materialized on the previous day with the victory over Ajax, only the mathematical conquest of the first place in the group is missing because the victory of Liverpool in Amsterdam postpones the final verdict to the direct match in the program. on the last day Tuesday of next week at Anfield. For Napoli it will be enough not to be defeated by Liverpool with more than three goals to qualify for first place and to be able to hope for a more favorable draw.
The game with Rangers has practically no history. Despite Spalletti initially leaving important players such as Osimhen, Kvaratskhelia, Lozano, Zielinski, Anguissa and Juan Jesus on the bench, the technical-tactical differences with the Scots turn out to be enormous. Napoli leads the game at will and after a quarter of an hour from the start of the match they are already ahead by two goals, thanks to a brace from Simeone, who bags at 10 ‘with a diagonal from the right and at 15’ with a diving header. The game mechanics of Spalletti’s team remain unchanged despite the numerous changes compared to the basic line-up.
The maneuver is always fluid and ball possession is suffocating for the opponents. The Rangers are constantly attacked when they are preparing to start the maneuver and fail to propose offensive maneuvers that can put the rearguard of the hosts in difficulty. In the second half, Napoli pays more attention to administering the advantage without wasting too much energy and the Scots face in some circumstances in the penalty area but fail to create problems for Meret.
Spalletti makes all the substitutions he has available and also gives a presence in the Champions League to some young players of the squad such as Gaetano, Zerbin and Zanoli. The Azzurri scored the third goal ten minutes from the end of the match. On the cross from the flag of Raspadori stands Ostigard in the penalty area who hits his head and sends the ball into the net. It ends with yet another success. In Liverpool the last act of the first phase of the Champions League will take place in which Napoli is proceeding in forced marches and as a true dominator.
)
[2] => Array
(
[title] => We need to stop thinking of insects as ‘creepy crawlies’ and recognize their keystone role in ecosystems
[link] => https://coolnspicy.com/healthandscience/we-need-to-stop-thinking-of-insects-as-creepy-crawlies-and-recognize-their-keystone-role-in-ecosystems/
[dc] => Array
(
[creator] => Tony Grantly
)
[pubdate] => Mon, 31 Oct 2022 10:19:40 +0000
[category] => Health And SciencecrawliesCreepyecosystemsinsectskeystonerecognizerolethinking
[guid] => https://coolnspicy.com/?p=55864
[description] => Journal Reference: Philip Donkersley, Louise Ashton, Greg P. A. Lamarre, Simon Segar. Global insect decline is the result of wilful political failure: A battle plan for entomology. Ecology and Evolution, 2022; 12 (10) DOI: 10.1002/ece3.9417 The widespread and deeply ingrained cultural perception of insects as creepy crawlies is a key factor holding back the public’s appreciation ... Read more
[content] => Array
(
[encoded] =>
Journal Reference:
Philip Donkersley, Louise Ashton, Greg P. A. Lamarre, Simon Segar. Global insect decline is the result of wilful political failure: A battle plan for entomology. Ecology and Evolution, 2022; 12 (10) DOI: 10.1002/ece3.9417
The widespread and deeply ingrained cultural perception of insects as creepy crawlies is a key factor holding back the public’s appreciation of the role they play within ecosystems. This perception is in part reflected in government biodiversity policy inaction across the globe, they argue.
This point is among a range of actions highlighted as part of a new paper published in Ecology and Evolution produced by an international team of entomologists which outlines a ‘battle plan’ including steps needed to prevent further insect losses across the globe.
Led by Dr Philip Donkersley of Lancaster University and co-authored by scientists from the University of Hong Kong, the Czech Academy of Sciences and Harper Adams University, the paper is a call to action targeted at other entomologists to step up advocacy for insects.
Despite 30 years of intergovernmental reports highlighting biodiversity targets, global insect abundance, biomass and diversity continues to decline. The paper considers the lack of progress in protecting insects and why meaningful change has not happened.
“Biodiversity, including insect, declines are often unintended consequences of human activities with human wellbeing nearly always trumping nature conservation, and this is likely to continue until we reach a point where we see flat-lining ecosystems are detrimental to our own species,” said Dr Donkersley. “Intergovernmental action has been slow to respond, kicking in only when change becomes impossible to ignore. If we are to see political attitudes and actions change then first societies’ perception of insects needs to be addressed.”
The paper highlights the range of benefits that insects bring, including some that are lesser known. These benefits include fundamental roles within ecosystems through interactions with plants including as pollinators, as a food for other animals, and as a food source for people in many parts of the world. Other benefits the authors highlight include insects’ contributions to wellbeing, culture and innovation, such as the benefits people derive from seeing butterflies in parks and gardens, their inclusion in poetry and literature, and their inspiration for a range of technologies, cosmetics and pharmaceuticals.
The researchers have outlined strategic priorities in their action plan to help support the conservation of insects. These include:
to proactively and publicly address government inaction
highlighting the technological developments we owe to the insects, and that there is a lot still to be discovered
aligning with bird, plant and mammal conservation groups to show species interdependencies and knock-on benefits insect conservation has for other animals
Engage public and school students with the wonders of the insect world to counter perceptions of insects as threatening ‘creepy crawlies’
“The benefits we gain from the insect world are broad, yet aversion of phobias of invertebrates are common and stand firmly in the path of their conservation,” said Dr Donkersley. “We need to move beyond this mindset and appreciate the huge role they play in ecosystems, foodchains, mental health, and even technological innovation.
“This perception change is a crucial step, alongside other measures we outline in this paper. Immediate and substantial actions are needed to protect insect species in order to maintain global ecosystem stability.”
The steps are outlined in the paper ‘Global insect decline is the result of wilful political failure: A battle plan for entomology’.
Authors on the paper are Dr Philip Donkersley, Lancaster University, Dr Louise Ashton, University of Hong Kong, Dr Greg Lamarre, Czech Academy of Sciences, and Dr Simon Segar, Harper Adams University.
We wish to give thanks to the author of this short article for this remarkable web content
)
[summary] => Journal Reference: Philip Donkersley, Louise Ashton, Greg P. A. Lamarre, Simon Segar. Global insect decline is the result of wilful political failure: A battle plan for entomology. Ecology and Evolution, 2022; 12 (10) DOI: 10.1002/ece3.9417 The widespread and deeply ingrained cultural perception of insects as creepy crawlies is a key factor holding back the public’s appreciation ... Read more
[atom_content] =>
Journal Reference:
Philip Donkersley, Louise Ashton, Greg P. A. Lamarre, Simon Segar. Global insect decline is the result of wilful political failure: A battle plan for entomology. Ecology and Evolution, 2022; 12 (10) DOI: 10.1002/ece3.9417
The widespread and deeply ingrained cultural perception of insects as creepy crawlies is a key factor holding back the public’s appreciation of the role they play within ecosystems. This perception is in part reflected in government biodiversity policy inaction across the globe, they argue.
This point is among a range of actions highlighted as part of a new paper published in Ecology and Evolution produced by an international team of entomologists which outlines a ‘battle plan’ including steps needed to prevent further insect losses across the globe.
Led by Dr Philip Donkersley of Lancaster University and co-authored by scientists from the University of Hong Kong, the Czech Academy of Sciences and Harper Adams University, the paper is a call to action targeted at other entomologists to step up advocacy for insects.
Despite 30 years of intergovernmental reports highlighting biodiversity targets, global insect abundance, biomass and diversity continues to decline. The paper considers the lack of progress in protecting insects and why meaningful change has not happened.
“Biodiversity, including insect, declines are often unintended consequences of human activities with human wellbeing nearly always trumping nature conservation, and this is likely to continue until we reach a point where we see flat-lining ecosystems are detrimental to our own species,” said Dr Donkersley. “Intergovernmental action has been slow to respond, kicking in only when change becomes impossible to ignore. If we are to see political attitudes and actions change then first societies’ perception of insects needs to be addressed.”
The paper highlights the range of benefits that insects bring, including some that are lesser known. These benefits include fundamental roles within ecosystems through interactions with plants including as pollinators, as a food for other animals, and as a food source for people in many parts of the world. Other benefits the authors highlight include insects’ contributions to wellbeing, culture and innovation, such as the benefits people derive from seeing butterflies in parks and gardens, their inclusion in poetry and literature, and their inspiration for a range of technologies, cosmetics and pharmaceuticals.
The researchers have outlined strategic priorities in their action plan to help support the conservation of insects. These include:
to proactively and publicly address government inaction
highlighting the technological developments we owe to the insects, and that there is a lot still to be discovered
aligning with bird, plant and mammal conservation groups to show species interdependencies and knock-on benefits insect conservation has for other animals
Engage public and school students with the wonders of the insect world to counter perceptions of insects as threatening ‘creepy crawlies’
“The benefits we gain from the insect world are broad, yet aversion of phobias of invertebrates are common and stand firmly in the path of their conservation,” said Dr Donkersley. “We need to move beyond this mindset and appreciate the huge role they play in ecosystems, foodchains, mental health, and even technological innovation.
“This perception change is a crucial step, alongside other measures we outline in this paper. Immediate and substantial actions are needed to protect insect species in order to maintain global ecosystem stability.”
The steps are outlined in the paper ‘Global insect decline is the result of wilful political failure: A battle plan for entomology’.
Authors on the paper are Dr Philip Donkersley, Lancaster University, Dr Louise Ashton, University of Hong Kong, Dr Greg Lamarre, Czech Academy of Sciences, and Dr Simon Segar, Harper Adams University.
We wish to give thanks to the author of this short article for this remarkable web content
)
[3] => Array
(
[title] => Sticking together without stickiness
[link] => https://coolnspicy.com/healthandscience/sticking-together-without-stickiness/
[dc] => Array
(
[creator] => Tony Grantly
)
[pubdate] => Mon, 31 Oct 2022 09:03:39 +0000
[category] => Health And SciencestickinessSticking
[guid] => https://coolnspicy.com/?p=55859
[description] => Journal Reference: Matthew W. Cotton, Ramin Golestanian, Jaime Agudo-Canalejo. Catalysis-Induced Phase Separation and Autoregulation of Enzymatic Activity. Physical Review Letters, 2022; 129 (15) DOI: 10.1103/PhysRevLett.129.158101 Traditionally, cellular organelles defined by a membrane have been considered the functional units of a cell. In recent years, it was shown that also molecular droplets formed inside the cell ... Read more
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(
[encoded] =>
Journal Reference:
Matthew W. Cotton, Ramin Golestanian, Jaime Agudo-Canalejo. Catalysis-Induced Phase Separation and Autoregulation of Enzymatic Activity. Physical Review Letters, 2022; 129 (15) DOI: 10.1103/PhysRevLett.129.158101
Traditionally, cellular organelles defined by a membrane have been considered the functional units of a cell. In recent years, it was shown that also molecular droplets formed inside the cell provide a micro-environment for important reactions. Such droplets are not enclosed by a membrane, and arise from phase separation. Hence, they form dynamically and can be regulated according to the needs of the cell.
Nonequilibrium drives can induce droplet formation
In the department of Living Matter Physics, managing director Ramin Golestanian and coworkers aim to reveal the organizational principles of living matter. “The formation of droplets in cells so far was ascribed to attractive, sticky interactions between molecules — similar to how droplets form in non-living, equilibrium systems, such as droplets of oil in a vinaigrette,” explains Jaime Agudo-Canalejo, group leader at the MPI-DS. “We now found that the nonequilibrium drive provided by enzymatic reactions can cause the formation of enzyme-rich droplets, even without any stickiness. Instead, the enzymes are pushed against each other by the chemical fluxes they create” he continues.
The researchers explored this novel mechanism by formulating a model in which the effect of a multicomponent enzymatic reaction on the micro-environment is described. They also considered the underlying feedback mechanism due to which the induced phase separation can in turn affect the initial enzymatic reaction. “When the enzymatic activity gets too intense, phase separation occurs and acts to reduce it, providing a new form of autoregulation,” says Matthew Cotton, first author of the study. This complex interplay of molecular interactions can provide a dynamic environment for cellular processes. Hence, the model adds another piece to the complex puzzle of how life is able to organize itself.
We want to say thanks to the writer of this write-up for this amazing web content
)
[summary] => Journal Reference: Matthew W. Cotton, Ramin Golestanian, Jaime Agudo-Canalejo. Catalysis-Induced Phase Separation and Autoregulation of Enzymatic Activity. Physical Review Letters, 2022; 129 (15) DOI: 10.1103/PhysRevLett.129.158101 Traditionally, cellular organelles defined by a membrane have been considered the functional units of a cell. In recent years, it was shown that also molecular droplets formed inside the cell ... Read more
[atom_content] =>
Journal Reference:
Matthew W. Cotton, Ramin Golestanian, Jaime Agudo-Canalejo. Catalysis-Induced Phase Separation and Autoregulation of Enzymatic Activity. Physical Review Letters, 2022; 129 (15) DOI: 10.1103/PhysRevLett.129.158101
Traditionally, cellular organelles defined by a membrane have been considered the functional units of a cell. In recent years, it was shown that also molecular droplets formed inside the cell provide a micro-environment for important reactions. Such droplets are not enclosed by a membrane, and arise from phase separation. Hence, they form dynamically and can be regulated according to the needs of the cell.
Nonequilibrium drives can induce droplet formation
In the department of Living Matter Physics, managing director Ramin Golestanian and coworkers aim to reveal the organizational principles of living matter. “The formation of droplets in cells so far was ascribed to attractive, sticky interactions between molecules — similar to how droplets form in non-living, equilibrium systems, such as droplets of oil in a vinaigrette,” explains Jaime Agudo-Canalejo, group leader at the MPI-DS. “We now found that the nonequilibrium drive provided by enzymatic reactions can cause the formation of enzyme-rich droplets, even without any stickiness. Instead, the enzymes are pushed against each other by the chemical fluxes they create” he continues.
The researchers explored this novel mechanism by formulating a model in which the effect of a multicomponent enzymatic reaction on the micro-environment is described. They also considered the underlying feedback mechanism due to which the induced phase separation can in turn affect the initial enzymatic reaction. “When the enzymatic activity gets too intense, phase separation occurs and acts to reduce it, providing a new form of autoregulation,” says Matthew Cotton, first author of the study. This complex interplay of molecular interactions can provide a dynamic environment for cellular processes. Hence, the model adds another piece to the complex puzzle of how life is able to organize itself.
We want to say thanks to the writer of this write-up for this amazing web content
)
[4] => Array
(
[title] => Arnold Schwarzenegger Finally Opens Up Bromance With Rival Sylvester Stallone in Their 70’s: “Nothing Is Zero Sum”
[link] => https://coolnspicy.com/trending-people/arnold-schwarzenegger-finally-opens-up-bromance-with-rival-sylvester-stallone-in-their-70s-nothing-is-zero-sum/
[dc] => Array
(
[creator] => Pauline Moonlky
)
[pubdate] => Mon, 31 Oct 2022 07:54:09 +0000
[category] => Trending People70sArnoldBromanceFinallyrivalSchwarzeneggerStalloneSumSylvester
[guid] => https://coolnspicy.com/?p=55853
[description] => Whether it is rivalry or camaraderie, Arnold Schwarzenegger, and Sylvester Stallone, do it with style. Are they setting serious bromance goals? Of course, yes! While the scenario now is the two legends posing with each other’s iconic swords, sporting a cow-boy look, one can’t forget the competitiveness they had in their prime phase. Schwarzenegger and ... Read more
[content] => Array
(
[encoded] =>
Whether it is rivalry or camaraderie, Arnold Schwarzenegger, and Sylvester Stallone, do it with style. Are they setting serious bromance goals? Of course, yes! While the scenario now is the two legends posing with each other’s iconic swords, sporting a cow-boy look, one can’t forget the competitiveness they had in their prime phase. Schwarzenegger and Stallone became synonymous with action heroes with their blockbuster hits from The Terminator, and Rocky franchises.
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In their 70s now, their bromance is making waves on the internet. Arnie and Sly first met at the 1977 Golden Globe ceremony, and an event of Stallone throwing a bowl of flowers at Schwarzenegger created a deep impact on their relationship. Soon after, they were often compared with each other at every step. The burning rage calmed down in the late ‘90s as their impact reduced in Hollywood. In Arnold’s recent newsletter, he shared an insightful note on bonding with Sly.
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Arnold Schwarzenegger roots the idea of being friends with a competitor
Arnold Schwarzenegger and Sylvester Stallone made Halloween more special, as their friendship was witnessed, while they carved pumpkins like kids. In the newsletter, Schwarzenegger mentioned that Sly asked him to film with him for his show. Besides, he also invited Sly to visit his office as he had never been there. Surprising him with Whiskey and Lulu and carving a pumpkin like kids, they made beautiful memories.
Reflecting on their days as rivals, he poured his heart out on the idea of competition. He said it is good as it creates better performances. “But unless you are competing in a sport where you either win or lose, nothing is zero sum.” Furthermore, he said about having a broader perspective stating, “There is plenty of pie to go around.”
Speaking particularly about Sly and his rivalry, he said, “You can be successful and still root for the guy two desks down to be successful.” He also said that it took them a few decades to figure out “we could both succeed and be friends and, man, it is so much better.”
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Arnie and Sly – foes to friends
Talking more about their intense rivalry and the time spent together, the Arnold Schwarzenegger further stated, “We had a fantastic time, and I do think there is a lesson there.” Moreover, he made an interesting point stating that thirty years ago, such a thing would have never happened. “Our egos wouldn’t allow it,” he said. Also, being in their mid-’70s, he said, “None of that sh** matters to us any more.”
LOS ANGELES, CA – SEPTEMBER 26: Actor Sylvester Stallone and California Governor Arnold Schwarzenegger attend the WBC World Championship Heavyweight fight between Vitali Klitschko of Ukraine and Chris Arreloa at the Staples Center on September 26, 2009 in Los Angeles, California. (Photo by Donald Miralle/Bongarts/Getty Images)
Arnie and Sly have exchanged comments and criticism on several occasions. That also implied that they strived hard to beat one another, at every opportunity they got. From being intense rivals to embracing the idea of supporting and cheering for each other, the two stars are setting an example of competitors co-existing without having to pull each other down.
)
[summary] => Whether it is rivalry or camaraderie, Arnold Schwarzenegger, and Sylvester Stallone, do it with style. Are they setting serious bromance goals? Of course, yes! While the scenario now is the two legends posing with each other’s iconic swords, sporting a cow-boy look, one can’t forget the competitiveness they had in their prime phase. Schwarzenegger and ... Read more
[atom_content] =>
Whether it is rivalry or camaraderie, Arnold Schwarzenegger, and Sylvester Stallone, do it with style. Are they setting serious bromance goals? Of course, yes! While the scenario now is the two legends posing with each other’s iconic swords, sporting a cow-boy look, one can’t forget the competitiveness they had in their prime phase. Schwarzenegger and Stallone became synonymous with action heroes with their blockbuster hits from The Terminator, and Rocky franchises.
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In their 70s now, their bromance is making waves on the internet. Arnie and Sly first met at the 1977 Golden Globe ceremony, and an event of Stallone throwing a bowl of flowers at Schwarzenegger created a deep impact on their relationship. Soon after, they were often compared with each other at every step. The burning rage calmed down in the late ‘90s as their impact reduced in Hollywood. In Arnold’s recent newsletter, he shared an insightful note on bonding with Sly.
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Article continues below this ad
Arnold Schwarzenegger roots the idea of being friends with a competitor
Arnold Schwarzenegger and Sylvester Stallone made Halloween more special, as their friendship was witnessed, while they carved pumpkins like kids. In the newsletter, Schwarzenegger mentioned that Sly asked him to film with him for his show. Besides, he also invited Sly to visit his office as he had never been there. Surprising him with Whiskey and Lulu and carving a pumpkin like kids, they made beautiful memories.
Reflecting on their days as rivals, he poured his heart out on the idea of competition. He said it is good as it creates better performances. “But unless you are competing in a sport where you either win or lose, nothing is zero sum.” Furthermore, he said about having a broader perspective stating, “There is plenty of pie to go around.”
Speaking particularly about Sly and his rivalry, he said, “You can be successful and still root for the guy two desks down to be successful.” He also said that it took them a few decades to figure out “we could both succeed and be friends and, man, it is so much better.”
ADVERTISEMENT
Article continues below this ad
Arnie and Sly – foes to friends
Talking more about their intense rivalry and the time spent together, the Arnold Schwarzenegger further stated, “We had a fantastic time, and I do think there is a lesson there.” Moreover, he made an interesting point stating that thirty years ago, such a thing would have never happened. “Our egos wouldn’t allow it,” he said. Also, being in their mid-’70s, he said, “None of that sh** matters to us any more.”
LOS ANGELES, CA – SEPTEMBER 26: Actor Sylvester Stallone and California Governor Arnold Schwarzenegger attend the WBC World Championship Heavyweight fight between Vitali Klitschko of Ukraine and Chris Arreloa at the Staples Center on September 26, 2009 in Los Angeles, California. (Photo by Donald Miralle/Bongarts/Getty Images)
Arnie and Sly have exchanged comments and criticism on several occasions. That also implied that they strived hard to beat one another, at every opportunity they got. From being intense rivals to embracing the idea of supporting and cheering for each other, the two stars are setting an example of competitors co-existing without having to pull each other down.
)
[5] => Array
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[title] => Researchers Vincenzo Fogliano and Harry Wichers on fresh – A two-year-old can of beans is more sustainable and nutritious – Foodlog
[link] => https://coolnspicy.com/magazine/researchers-vincenzo-fogliano-and-harry-wichers-on-fresh-a-two-year-old-can-of-beans-is-more-sustainable-and-nutritious-foodlog/
[dc] => Array
(
[creator] => Pauline Moonlky
)
[pubdate] => Mon, 31 Oct 2022 07:52:50 +0000
[category] => MagazineBeansFoglianoFoodlogfreshHarrynutritiousResearcherssustainabletwoyearoldVincenzoWichers
[guid] => https://coolnspicy.com/?p=55848
[description] => There are few words in the voluminous food glossary with a positive connotation that compare to ‘fresh’. Whatever product we plan to eat, the general feeling is that an inevitable process of deterioration kicks in as soon as something is harvested. Think of the breakdown of nutrients, loss of tasty taste and the development of ... Read more
[content] => Array
(
[encoded] =>
There are few words in the voluminous food glossary with a positive connotation that compare to ‘fresh’. Whatever product we plan to eat, the general feeling is that an inevitable process of deterioration kicks in as soon as something is harvested. Think of the breakdown of nutrients, loss of tasty taste and the development of deviant taste, not to mention the growth of all kinds of nasty (pathological) germs!
Mythen over vers Food technologists know that there are all kinds of myths associated with the supposed quality of ‘freshly harvested’, ‘freshly baked’, ‘freshly prepared’, ‘freshly caught fish’, in ‘fresh’ water of course! It would be wise to at least make a distinction for yourself and not to overestimate products so that you will pay too much for them. Because unfortunately, products are simply marketed as ‘fresh’ to suggest added value.
It may sound provocative, but a two-year-old can of beans is an excellent choice from a nutritional, sensory, and even environmental standpoint.
Through expert storage and preservation, the industry is in an excellent position to maintain the quality parameters of fresh products. Many of the fruits and vegetables you find in supermarkets are as good as ‘freshly’ harvested. The same goes for the necessary processed products such as milk, olive oil, nuts, cheese and meat. They have a taste, texture and color comparable to fresh products and, viewed objectively, are of even better quality than the corresponding fresh products, for example because they are safer.
Good fresh often man made Of course there are situations in which the adage fresh=good applies; interestingly enough, these are mostly man-made products, such as bread and other baked goods. In addition, there are also plenty of examples of matured products that improve their quality through storage. Think wine, cheese and ham, to name a few.
We can imagine that, if you grow your own vegetables in a vegetable garden, you read this shaking your head. You were just as excited about the crunchiness of your lettuce! We are sorry to tell you that you are a little biased by the joy of gardening. People around you usually like the supermarket product better than yours… but they are just too nice to tell you that!
Freshly picked has few benefits Picking fruit straight from the tree (assuming you’re lucky enough to be there at just the right time) is a fantastic experience. Only, in most cases, there are no ‘freshness benefits’. Citrus fruits, apples, kiwis and berries are just as good as freshly picked, if stored properly!
Perhaps the most important thing we want to tell you is this: be aware that ‘fresh’ comes with environmental consequences. Transporting fresh products costs energy, while the limited shelf life causes food waste. It may sound provocative, but a two-year-old can of beans is an excellent choice from a nutritional, sensory, and even environmental standpoint.
In What’s …? together with well-known and lesser-known people, we look for what motivates them to discover whether we can find each other again from there. You can read why we do that in The discovery of the other.
We wish to say thanks to the author of this short article for this amazing content
)
[summary] => There are few words in the voluminous food glossary with a positive connotation that compare to ‘fresh’. Whatever product we plan to eat, the general feeling is that an inevitable process of deterioration kicks in as soon as something is harvested. Think of the breakdown of nutrients, loss of tasty taste and the development of ... Read more
[atom_content] =>
There are few words in the voluminous food glossary with a positive connotation that compare to ‘fresh’. Whatever product we plan to eat, the general feeling is that an inevitable process of deterioration kicks in as soon as something is harvested. Think of the breakdown of nutrients, loss of tasty taste and the development of deviant taste, not to mention the growth of all kinds of nasty (pathological) germs!
Mythen over vers Food technologists know that there are all kinds of myths associated with the supposed quality of ‘freshly harvested’, ‘freshly baked’, ‘freshly prepared’, ‘freshly caught fish’, in ‘fresh’ water of course! It would be wise to at least make a distinction for yourself and not to overestimate products so that you will pay too much for them. Because unfortunately, products are simply marketed as ‘fresh’ to suggest added value.
It may sound provocative, but a two-year-old can of beans is an excellent choice from a nutritional, sensory, and even environmental standpoint.
Through expert storage and preservation, the industry is in an excellent position to maintain the quality parameters of fresh products. Many of the fruits and vegetables you find in supermarkets are as good as ‘freshly’ harvested. The same goes for the necessary processed products such as milk, olive oil, nuts, cheese and meat. They have a taste, texture and color comparable to fresh products and, viewed objectively, are of even better quality than the corresponding fresh products, for example because they are safer.
Good fresh often man made Of course there are situations in which the adage fresh=good applies; interestingly enough, these are mostly man-made products, such as bread and other baked goods. In addition, there are also plenty of examples of matured products that improve their quality through storage. Think wine, cheese and ham, to name a few.
We can imagine that, if you grow your own vegetables in a vegetable garden, you read this shaking your head. You were just as excited about the crunchiness of your lettuce! We are sorry to tell you that you are a little biased by the joy of gardening. People around you usually like the supermarket product better than yours… but they are just too nice to tell you that!
Freshly picked has few benefits Picking fruit straight from the tree (assuming you’re lucky enough to be there at just the right time) is a fantastic experience. Only, in most cases, there are no ‘freshness benefits’. Citrus fruits, apples, kiwis and berries are just as good as freshly picked, if stored properly!
Perhaps the most important thing we want to tell you is this: be aware that ‘fresh’ comes with environmental consequences. Transporting fresh products costs energy, while the limited shelf life causes food waste. It may sound provocative, but a two-year-old can of beans is an excellent choice from a nutritional, sensory, and even environmental standpoint.
In What’s …? together with well-known and lesser-known people, we look for what motivates them to discover whether we can find each other again from there. You can read why we do that in The discovery of the other.
We wish to say thanks to the author of this short article for this amazing content
)
[6] => Array
(
[title] => Certain type of stroke on the rise, with higher rates among Black people
[link] => https://coolnspicy.com/healthandscience/certain-type-of-stroke-on-the-rise-with-higher-rates-among-black-people/
[dc] => Array
(
[creator] => Tony Grantly
)
[pubdate] => Mon, 31 Oct 2022 07:46:02 +0000
[category] => Health And ScienceblackPeopleratesrisestrokeType
[guid] => https://coolnspicy.com/?p=55843
[description] => Journal Reference: Christina Xia, Haydn Hoffman, Nnabuchi Anikpezie, Karan Philip, Claribel Wee, Reema Choudhry, Karen C. Albright, Hesham Masoud, Timothy Beutler, Elena Schmidt, Grahame Gould, Smit D. Patel, Emmanuel Oladele Akano, Nicholas Morris, Seemant Chaturvedi, Ehimen Aneni, Oluwatomi Lamikanra, Lawrence Chin, Julius G. Latorre, Fadar Oliver Otite. Trends in the Incidence of Spontaneous Subarachnoid Hemorrhages ... Read more
[content] => Array
(
[encoded] =>
Journal Reference:
Christina Xia, Haydn Hoffman, Nnabuchi Anikpezie, Karan Philip, Claribel Wee, Reema Choudhry, Karen C. Albright, Hesham Masoud, Timothy Beutler, Elena Schmidt, Grahame Gould, Smit D. Patel, Emmanuel Oladele Akano, Nicholas Morris, Seemant Chaturvedi, Ehimen Aneni, Oluwatomi Lamikanra, Lawrence Chin, Julius G. Latorre, Fadar Oliver Otite. Trends in the Incidence of Spontaneous Subarachnoid Hemorrhages in the United States, 2007–2017. Neurology, 2022; 10.1212/WNL.0000000000201340 DOI: 10.1212/WNL.0000000000201340
A subarachnoid hemorrhage is when bleeding occurs, usually from a burst blood vessel, in the space between the brain and the membrane that covers it. This type of stroke can be caused by a rupture of an aneurysm, high blood pressure or trauma. For this study, researchers looked only at those not caused by trauma.
“Subarachnoid hemorrhages unrelated to trauma account for 5% to 10% of all strokes in the United States, and are often deadly,” said study author Fadar Oliver Otite, M.D., Sc.M., of the SUNY Upstate Medical University in Syracuse, N.Y. “Not only did we find an increase in these strokes over recent years, we also found the incidence was disproportionally higher and increasing in Black people while rates did not increase in people of other races and ethnicities.”
For the study, researchers reviewed state hospitalization databases for New York and Florida and identified 39,475 people hospitalized for non-traumatic subarachnoid hemorrhage between 2007 and 2017. Using Census data, they then calculated the annual rates of this type of stroke in those states and compared those rates over time for men, women, various age ranges, races and ethnicities.
Researchers found that over the 10-year study, the average incidence of this type of stroke for all participants was 11 cases per 100,000 people. Rates were higher in women with 13 cases per 100,000 people, and lower in men with 10 cases. Incidence also increased with age. For middle-aged men, the average was four cases per 100,000 people while for men 65 and older, the average was 22 cases. Incidence increased over time, by 0.7% on average per year overall, with most of the increase in middle-aged men at 1.1%, older men at 2.3% and older women at 0.7%, while the incidence in young women declined by 0.7%.
When looking at race and ethnicity, researchers found incidence was greater in Black people with an average of 15 cases per 100,000 people compared to non-Hispanic white people with an average of 10 cases.
Incidence increased in Black people by 1.8% per year while rates for Hispanic, Asian and non-Hispanic white people did not change over time.
“The incidence of this type of stroke is disproportionately higher, and increasing, in Black people, leading to a widening of the racial incidence gap,” said Otite. “Previous studies have found Black people develop high blood pressure younger and are more likely to have uncontrolled high blood pressure than non-Hispanic white people, so expanding efforts to control blood pressure may help reduce rates.The causes also likely extend to socioeconomic factors including structural racism. Tackling racial disparities will require multifaceted interventions targeted at stroke risk factors and socioeconomic inequity.”
A limitation of the study was researchers were unable to differentiate between strokes caused by aneurysms and those not caused by aneurysms, which would have provided further insight.
We would love to say thanks to the author of this short article for this remarkable material
)
[summary] => Journal Reference: Christina Xia, Haydn Hoffman, Nnabuchi Anikpezie, Karan Philip, Claribel Wee, Reema Choudhry, Karen C. Albright, Hesham Masoud, Timothy Beutler, Elena Schmidt, Grahame Gould, Smit D. Patel, Emmanuel Oladele Akano, Nicholas Morris, Seemant Chaturvedi, Ehimen Aneni, Oluwatomi Lamikanra, Lawrence Chin, Julius G. Latorre, Fadar Oliver Otite. Trends in the Incidence of Spontaneous Subarachnoid Hemorrhages ... Read more
[atom_content] =>
Journal Reference:
Christina Xia, Haydn Hoffman, Nnabuchi Anikpezie, Karan Philip, Claribel Wee, Reema Choudhry, Karen C. Albright, Hesham Masoud, Timothy Beutler, Elena Schmidt, Grahame Gould, Smit D. Patel, Emmanuel Oladele Akano, Nicholas Morris, Seemant Chaturvedi, Ehimen Aneni, Oluwatomi Lamikanra, Lawrence Chin, Julius G. Latorre, Fadar Oliver Otite. Trends in the Incidence of Spontaneous Subarachnoid Hemorrhages in the United States, 2007–2017. Neurology, 2022; 10.1212/WNL.0000000000201340 DOI: 10.1212/WNL.0000000000201340
A subarachnoid hemorrhage is when bleeding occurs, usually from a burst blood vessel, in the space between the brain and the membrane that covers it. This type of stroke can be caused by a rupture of an aneurysm, high blood pressure or trauma. For this study, researchers looked only at those not caused by trauma.
“Subarachnoid hemorrhages unrelated to trauma account for 5% to 10% of all strokes in the United States, and are often deadly,” said study author Fadar Oliver Otite, M.D., Sc.M., of the SUNY Upstate Medical University in Syracuse, N.Y. “Not only did we find an increase in these strokes over recent years, we also found the incidence was disproportionally higher and increasing in Black people while rates did not increase in people of other races and ethnicities.”
For the study, researchers reviewed state hospitalization databases for New York and Florida and identified 39,475 people hospitalized for non-traumatic subarachnoid hemorrhage between 2007 and 2017. Using Census data, they then calculated the annual rates of this type of stroke in those states and compared those rates over time for men, women, various age ranges, races and ethnicities.
Researchers found that over the 10-year study, the average incidence of this type of stroke for all participants was 11 cases per 100,000 people. Rates were higher in women with 13 cases per 100,000 people, and lower in men with 10 cases. Incidence also increased with age. For middle-aged men, the average was four cases per 100,000 people while for men 65 and older, the average was 22 cases. Incidence increased over time, by 0.7% on average per year overall, with most of the increase in middle-aged men at 1.1%, older men at 2.3% and older women at 0.7%, while the incidence in young women declined by 0.7%.
When looking at race and ethnicity, researchers found incidence was greater in Black people with an average of 15 cases per 100,000 people compared to non-Hispanic white people with an average of 10 cases.
Incidence increased in Black people by 1.8% per year while rates for Hispanic, Asian and non-Hispanic white people did not change over time.
“The incidence of this type of stroke is disproportionately higher, and increasing, in Black people, leading to a widening of the racial incidence gap,” said Otite. “Previous studies have found Black people develop high blood pressure younger and are more likely to have uncontrolled high blood pressure than non-Hispanic white people, so expanding efforts to control blood pressure may help reduce rates.The causes also likely extend to socioeconomic factors including structural racism. Tackling racial disparities will require multifaceted interventions targeted at stroke risk factors and socioeconomic inequity.”
A limitation of the study was researchers were unable to differentiate between strokes caused by aneurysms and those not caused by aneurysms, which would have provided further insight.
We would love to say thanks to the author of this short article for this remarkable material
)
[7] => Array
(
[title] => Do you want to know why Omar Sy became ‘Lupin’?
[link] => https://coolnspicy.com/influential-people/do-you-want-to-know-why-omar-sy-became-lupin-2/
[dc] => Array
(
[creator] => Harold Kent
)
[pubdate] => Mon, 31 Oct 2022 07:28:31 +0000
[category] => Influential PeopleLupinOmar
[guid] => https://coolnspicy.com/?p=55837
[description] => He already nailed it with ‘Untouchable’, the film that opened the doors of Hollywood for him, but his version of this lovable thief has made him an internationally recognized face. Without giving up his origins, or his smile. He already works on the third season. He is a comedian from head to toe, one of ... Read more
[content] => Array
(
[encoded] =>
He already nailed it with ‘Untouchable’, the film that opened the doors of Hollywood for him, but his version of this lovable thief has made him an internationally recognized face. Without giving up his origins, or his smile. He already works on the third season.
He is a comedian from head to toe, one of those who does not stop imitating, telling jokes or sharpening everything. In fact, started in show business as part of a humorous duo, Omar and Fred. This Gallic actor of Senegalese origin, 1.90 tall and with a smile valued at a million dollars, raised in Trappes, a Parisian suburb, gave the chest do with “Untouchable” (2011), which in addition to earning him a César allowed him to move to Hollywood in 2012, along with his wife and five children. “I left to be just another black man,” she says jokingly. The media pressure on his family and his job offers pushed him to take the leap. ‘X-Men’, ‘Jurassic World 2 and 3’, ‘Inferno’, ‘Transformers’ have made it easier for him to gain a foothold there, without leaving French cinema, which has once again given him the keys to heaven.
Did you expect this answer, position yourself as the biggest French success of Netflix so far?
We wanted to show what the French were capable of when it came to making a series, but frankly, we did not expect such worldwide success. It reached 70 million homes in the first month of its premiere and has become the most watched series in 2021… We made television with the technique and bill of cinema, with a Hollywood director, Louis Leterrier (‘Transporter 2’, ‘Now You See Me’, ‘The Incredible Hulk’), who is a neighbor and friend. That is important.
The Frenchman enjoyed the enormous privilege of shooting in the Parisian Louvre and being alone with the ‘Mona Lisa’. | Emmanuel Guimier / Netflix
Are there differences between shooting series or film?
There is more rhythm in the series… At first, I suffered in my flesh (laughs), but looking back, I have fantastic memories. I learned a lot. I was taken out of my comfort zone and had to get used to new reference points… Especially shooting with different directors playing the same character.
How did this project come into your hands?
Gaumont, the producer, asked me a very simple but incredible question: Who would you like to play? I answered that Arsène Lupin, a perfect character for an actor: smart, charming, a guy who pretends to be other people, who allows you to experience adventures and go from drama to comedy and move towards the purest action… A candy.
Have you read Maurice Leblanc’s books?
Nope! My generation has done the reverse journey: first, we discovered the manga, and then we learned that it was based on a French novel. My first relationship with Lupine was in Japanese! I started reading the books when I joined this project and had to prepare for the role and found them very stimulating.
How do you see Assane, your character?
He’s a very smart guy, but believable. He didn’t want to make him gifted, especially since Lupine isn’t. He is a character with great logic and knowledge, not a superhero. Assane, like his model in the novel, understands how both society and people work. And that allows you to anticipate his decisions and reactions. He is a difficult guy to understand, because he is always evolving, he does not go in a straight line, he does not destroy everything, he dodges obstacles and passes from one character to another, he masters the art of evasion, but in a zig-zag! (laughs).
Assane is the character that Omar plays and that is governed by the ideas of the novel. | Emmanuel Guimier
Unlike the traditional Lupine, he never wears makeup, he maintains his appearance…
We wanted to avoid falling into extravagances and, in addition, that was very seen. You just have to get lost among a certain social class to disappear: you just have to pretend to be a street sweeper to make yourself invisible. Nowadays, a book is judged by its cover. We played with that idea.
Does it evolve from the first to the second season?
Until the fifth episode, Assane runs the show. In the sixth, however, he begins to experience situations that transform him. He grapples with his responsibilities as a father as he realizes his limits, which to me is a really cool thing to play. Suddenly, he questions everything, his own rules: he is a white-collar thief, who does not kill or engage in violence, but is that valid, is he on the right track?
It cost you a lot to find a version of the script that convinced you. What is there in George Kay’s story that would win the day?
The character is framed in our society, while there was something unique about him. His desire for revenge offered a good parallel with the literary character, there was coherence between the stories of Lupine and Assane. Also the theme of fatherhood and bequeathing things to the next generation transcend the story. He is a boy who wants to avenge his father but, at the same time, wants to stop obsessing about it to act as a father himself… while still being a white-collar thief, of course.
Of the characters that Assane impersonates, which one is your favorite?
The weirdo with the yellow hat from the third episode. There I began to savor what I was expecting when I agreed to be part of the series: I knew that I would feel the same pleasure in dressing up as when I did it in “SAV des émissions” (a comedy series on French TV). I tried to change the voice, the posture… it was great. Lupine is the best toy in the world!
And what is it like to shoot in a place like the Louvre?
It was nothing complicated. When they understood that the series was going to be seen all over the world, they made life easier for us. At one point, I realized that I was in the Mona Lisa room. I started the stopwatch and for 16 minutes I was alone with her. I don’t know anyone who’s had a date like that!
You also see a Paris with a lot of diversity…
The city is just like that, with its good and bad things. We try to avoid clichés and show her as she really is. Yes, the series was going to tour the world, but Parisians were also going to see it.
Outside the series, you have manifested yourself on your networks – in which you define yourself as “a human being” – about the racial problem. Does fame make you feel responsible to raise your voice?
Yes and no. I am only responsible for myself and sometimes people will try to put responsibilities on me that are not really mine, so you have to be aware of that. And I feel more comfortable expressing myself through art.
In the documentary “C’est ta chance”, recorded by Eric Hannezo, your humble origins are highlighted. Is that why you are so involved, along with Helen, your wife and social worker, in solidarity causes?
I owe a debt to society. As a child, I managed to get ahead with help from the French State, so I have to do my bit. We run the NGO Cékedubonheur, which helps hospitalized children and adolescents in France. And in Senegal, through the organic products company Siyah Organics, whose profits are used to fight viral diseases in sub-Saharan Africa.
ARSÈNE LUPIN: A HISTORICAL SAGA ‘MADE IN FRANCE’
The adventures of the robber gentleman are very popular in France, to the point of competing with Sherlock Holmes. The writer, Maurice Leblanc, author of more than 60 novels, created it in 1905 as a single story, although his success led him to write almost twenty books. This white-collar thief has appeared in many versions in theater, film and television, including manga and video games (Code: Realize, PS4).
The first novel by Maurice Leblanc, republished by Anaya. | Anaya
We would love to say thanks to the author of this short article for this amazing material
)
[summary] => He already nailed it with ‘Untouchable’, the film that opened the doors of Hollywood for him, but his version of this lovable thief has made him an internationally recognized face. Without giving up his origins, or his smile. He already works on the third season. He is a comedian from head to toe, one of ... Read more
[atom_content] =>
He already nailed it with ‘Untouchable’, the film that opened the doors of Hollywood for him, but his version of this lovable thief has made him an internationally recognized face. Without giving up his origins, or his smile. He already works on the third season.
He is a comedian from head to toe, one of those who does not stop imitating, telling jokes or sharpening everything. In fact, started in show business as part of a humorous duo, Omar and Fred. This Gallic actor of Senegalese origin, 1.90 tall and with a smile valued at a million dollars, raised in Trappes, a Parisian suburb, gave the chest do with “Untouchable” (2011), which in addition to earning him a César allowed him to move to Hollywood in 2012, along with his wife and five children. “I left to be just another black man,” she says jokingly. The media pressure on his family and his job offers pushed him to take the leap. ‘X-Men’, ‘Jurassic World 2 and 3’, ‘Inferno’, ‘Transformers’ have made it easier for him to gain a foothold there, without leaving French cinema, which has once again given him the keys to heaven.
Did you expect this answer, position yourself as the biggest French success of Netflix so far?
We wanted to show what the French were capable of when it came to making a series, but frankly, we did not expect such worldwide success. It reached 70 million homes in the first month of its premiere and has become the most watched series in 2021… We made television with the technique and bill of cinema, with a Hollywood director, Louis Leterrier (‘Transporter 2’, ‘Now You See Me’, ‘The Incredible Hulk’), who is a neighbor and friend. That is important.
The Frenchman enjoyed the enormous privilege of shooting in the Parisian Louvre and being alone with the ‘Mona Lisa’. | Emmanuel Guimier / Netflix
Are there differences between shooting series or film?
There is more rhythm in the series… At first, I suffered in my flesh (laughs), but looking back, I have fantastic memories. I learned a lot. I was taken out of my comfort zone and had to get used to new reference points… Especially shooting with different directors playing the same character.
How did this project come into your hands?
Gaumont, the producer, asked me a very simple but incredible question: Who would you like to play? I answered that Arsène Lupin, a perfect character for an actor: smart, charming, a guy who pretends to be other people, who allows you to experience adventures and go from drama to comedy and move towards the purest action… A candy.
Have you read Maurice Leblanc’s books?
Nope! My generation has done the reverse journey: first, we discovered the manga, and then we learned that it was based on a French novel. My first relationship with Lupine was in Japanese! I started reading the books when I joined this project and had to prepare for the role and found them very stimulating.
How do you see Assane, your character?
He’s a very smart guy, but believable. He didn’t want to make him gifted, especially since Lupine isn’t. He is a character with great logic and knowledge, not a superhero. Assane, like his model in the novel, understands how both society and people work. And that allows you to anticipate his decisions and reactions. He is a difficult guy to understand, because he is always evolving, he does not go in a straight line, he does not destroy everything, he dodges obstacles and passes from one character to another, he masters the art of evasion, but in a zig-zag! (laughs).
Assane is the character that Omar plays and that is governed by the ideas of the novel. | Emmanuel Guimier
Unlike the traditional Lupine, he never wears makeup, he maintains his appearance…
We wanted to avoid falling into extravagances and, in addition, that was very seen. You just have to get lost among a certain social class to disappear: you just have to pretend to be a street sweeper to make yourself invisible. Nowadays, a book is judged by its cover. We played with that idea.
Does it evolve from the first to the second season?
Until the fifth episode, Assane runs the show. In the sixth, however, he begins to experience situations that transform him. He grapples with his responsibilities as a father as he realizes his limits, which to me is a really cool thing to play. Suddenly, he questions everything, his own rules: he is a white-collar thief, who does not kill or engage in violence, but is that valid, is he on the right track?
It cost you a lot to find a version of the script that convinced you. What is there in George Kay’s story that would win the day?
The character is framed in our society, while there was something unique about him. His desire for revenge offered a good parallel with the literary character, there was coherence between the stories of Lupine and Assane. Also the theme of fatherhood and bequeathing things to the next generation transcend the story. He is a boy who wants to avenge his father but, at the same time, wants to stop obsessing about it to act as a father himself… while still being a white-collar thief, of course.
Of the characters that Assane impersonates, which one is your favorite?
The weirdo with the yellow hat from the third episode. There I began to savor what I was expecting when I agreed to be part of the series: I knew that I would feel the same pleasure in dressing up as when I did it in “SAV des émissions” (a comedy series on French TV). I tried to change the voice, the posture… it was great. Lupine is the best toy in the world!
And what is it like to shoot in a place like the Louvre?
It was nothing complicated. When they understood that the series was going to be seen all over the world, they made life easier for us. At one point, I realized that I was in the Mona Lisa room. I started the stopwatch and for 16 minutes I was alone with her. I don’t know anyone who’s had a date like that!
You also see a Paris with a lot of diversity…
The city is just like that, with its good and bad things. We try to avoid clichés and show her as she really is. Yes, the series was going to tour the world, but Parisians were also going to see it.
Outside the series, you have manifested yourself on your networks – in which you define yourself as “a human being” – about the racial problem. Does fame make you feel responsible to raise your voice?
Yes and no. I am only responsible for myself and sometimes people will try to put responsibilities on me that are not really mine, so you have to be aware of that. And I feel more comfortable expressing myself through art.
In the documentary “C’est ta chance”, recorded by Eric Hannezo, your humble origins are highlighted. Is that why you are so involved, along with Helen, your wife and social worker, in solidarity causes?
I owe a debt to society. As a child, I managed to get ahead with help from the French State, so I have to do my bit. We run the NGO Cékedubonheur, which helps hospitalized children and adolescents in France. And in Senegal, through the organic products company Siyah Organics, whose profits are used to fight viral diseases in sub-Saharan Africa.
ARSÈNE LUPIN: A HISTORICAL SAGA ‘MADE IN FRANCE’
The adventures of the robber gentleman are very popular in France, to the point of competing with Sherlock Holmes. The writer, Maurice Leblanc, author of more than 60 novels, created it in 1905 as a single story, although his success led him to write almost twenty books. This white-collar thief has appeared in many versions in theater, film and television, including manga and video games (Code: Realize, PS4).
The first novel by Maurice Leblanc, republished by Anaya. | Anaya
We would love to say thanks to the author of this short article for this amazing material
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[8] => Array
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[title] => Emilia Clarke, beyond ‘Game of Thrones’
[link] => https://coolnspicy.com/celebrity/emilia-clarke-beyond-game-of-thrones-2/
[dc] => Array
(
[creator] => Sally Scully
)
[pubdate] => Mon, 31 Oct 2022 07:09:30 +0000
[category] => CelebrityClarkeEmiliaGameThrones
[guid] => https://coolnspicy.com/?p=55832
[description] => He became a star thanks to Game of Thrones the HBO series in which she played Daenerys Targaryen. But shortly before audiences saw her character fight her first contests in the inaugural season, Clarke overcame a stroke. In 2019, he revealed in a text for The New Yorker titled A Battle For My Life that ... Read more
[content] => Array
(
[encoded] =>
He became a star thanks to Game of Thrones the HBO series in which she played Daenerys Targaryen. But shortly before audiences saw her character fight her first contests in the inaugural season, Clarke overcame a stroke.
In 2019, he revealed in a text for The New Yorker titled A Battle For My Life that he had suffered aneurysms in 2011 and 2013.
Recently, he has returned to speak of those episodes. “With the amount of my brain that is disabled, it is extraordinary that I am able to speak, eloquently at times, and live my life completely normally,” she recently said in an interview on Sunday Morningfrom the BBC.
With the amount of my brain that I have disabled, it is extraordinary that I am able to speak, eloquently at times, and live my life completely normally.
british actress He was born in 1986 in London and grew up with his parents and older brother in the countryside in Oxford. “I grew up with ducks in the garden and a stream,” he told Elle in 2017.
His father, who died in 2016, was a theater sound designer and his mother is a businesswoman. Both she and her brother went to a local boarding school. “I was very artistic and no one else was. They were all like lawyers playing tennis. I was lousy at tennis and I didn’t care about Law, ”she added.
After finishing school, where he had already participated in plays, he studied at the Drama Center in London. After graduating, Clarke combined her search for a space in acting with other jobs, such as at a museum or a call center.
In 2010 his big break came. “She was literally touching the sky to have an audition,” she told Harper’s Bazaar in 2015. Days later he learned that the role was his.
Never in a million years did I think ‘Game of Thrones’ was going to take off the way it did.
In April 2011, the first chapter of the series was broadcast, which became a television phenomenon. “Not in a million years did I think Game of Thrones it was going to take off like it did,” the actress assured The Hollywood Reporter seven years ago. His powerful character inspired the series the house of the dragonprequel to Game of Thrones that HBO will premiere on August 21.
In February 2011, while preparing for an exercise session, his head began to hurt intensely, he tried to continue training, but had to return to the locker room and from there to the hospital. She was diagnosed with subarachnoid hemorrhage and was transferred to another hospital for urgent surgery.
‘I didn’t remember my name’
Clarke suffered from aphasia during recovery: “My full name is Emilia Isobel Euphemia Rose Clarke. But now he couldn’t remember. Nonsense words came out of my mouth and I panicked. I have never experienced fear like that,” she wrote on The New Yorker.
My full name is Emilia Isobel Euphemia Rose Clarke. But now he couldn’t remember. Nonsense words came out of my mouth and I panicked. I had never experienced fear like that.
She could see the life that awaited her, she said, and thought it was not worth living: “I am an actress; I need to remember my phrases. Now she couldn’t remember my name.” A week after that, the aphasia subsided.
In 2013, the doctor saw that an aneurysm on the other side of his brain had doubled in size. The operation did not go as planned, she suffered a hemorrhage and if she was not operated on again, her chances of survival were slim. They intervened again, this time through her skull.
Based on their experiences, Clarke started a foundation called Same You, which provides support to people who have suffered brain injuries, a task that she combines with her work as an actress.
MATTHEW CASTLE EFE Reports On Twitter: @EFENoticias
We wish to say thanks to the author of this write-up for this remarkable web content
)
[summary] => He became a star thanks to Game of Thrones the HBO series in which she played Daenerys Targaryen. But shortly before audiences saw her character fight her first contests in the inaugural season, Clarke overcame a stroke. In 2019, he revealed in a text for The New Yorker titled A Battle For My Life that ... Read more
[atom_content] =>
He became a star thanks to Game of Thrones the HBO series in which she played Daenerys Targaryen. But shortly before audiences saw her character fight her first contests in the inaugural season, Clarke overcame a stroke.
In 2019, he revealed in a text for The New Yorker titled A Battle For My Life that he had suffered aneurysms in 2011 and 2013.
Recently, he has returned to speak of those episodes. “With the amount of my brain that is disabled, it is extraordinary that I am able to speak, eloquently at times, and live my life completely normally,” she recently said in an interview on Sunday Morningfrom the BBC.
With the amount of my brain that I have disabled, it is extraordinary that I am able to speak, eloquently at times, and live my life completely normally.
british actress He was born in 1986 in London and grew up with his parents and older brother in the countryside in Oxford. “I grew up with ducks in the garden and a stream,” he told Elle in 2017.
His father, who died in 2016, was a theater sound designer and his mother is a businesswoman. Both she and her brother went to a local boarding school. “I was very artistic and no one else was. They were all like lawyers playing tennis. I was lousy at tennis and I didn’t care about Law, ”she added.
After finishing school, where he had already participated in plays, he studied at the Drama Center in London. After graduating, Clarke combined her search for a space in acting with other jobs, such as at a museum or a call center.
In 2010 his big break came. “She was literally touching the sky to have an audition,” she told Harper’s Bazaar in 2015. Days later he learned that the role was his.
Never in a million years did I think ‘Game of Thrones’ was going to take off the way it did.
In April 2011, the first chapter of the series was broadcast, which became a television phenomenon. “Not in a million years did I think Game of Thrones it was going to take off like it did,” the actress assured The Hollywood Reporter seven years ago. His powerful character inspired the series the house of the dragonprequel to Game of Thrones that HBO will premiere on August 21.
In February 2011, while preparing for an exercise session, his head began to hurt intensely, he tried to continue training, but had to return to the locker room and from there to the hospital. She was diagnosed with subarachnoid hemorrhage and was transferred to another hospital for urgent surgery.
‘I didn’t remember my name’
Clarke suffered from aphasia during recovery: “My full name is Emilia Isobel Euphemia Rose Clarke. But now he couldn’t remember. Nonsense words came out of my mouth and I panicked. I have never experienced fear like that,” she wrote on The New Yorker.
My full name is Emilia Isobel Euphemia Rose Clarke. But now he couldn’t remember. Nonsense words came out of my mouth and I panicked. I had never experienced fear like that.
She could see the life that awaited her, she said, and thought it was not worth living: “I am an actress; I need to remember my phrases. Now she couldn’t remember my name.” A week after that, the aphasia subsided.
In 2013, the doctor saw that an aneurysm on the other side of his brain had doubled in size. The operation did not go as planned, she suffered a hemorrhage and if she was not operated on again, her chances of survival were slim. They intervened again, this time through her skull.
Based on their experiences, Clarke started a foundation called Same You, which provides support to people who have suffered brain injuries, a task that she combines with her work as an actress.
MATTHEW CASTLE EFE Reports On Twitter: @EFENoticias
We wish to say thanks to the author of this write-up for this remarkable web content
)
[9] => Array
(
[title] => Franco Gatti, his wife Stefania on Domenica In: “He did not let himself die and our son was not a drug addict”
[link] => https://coolnspicy.com/shows/franco-gatti-his-wife-stefania-on-domenica-in-he-did-not-let-himself-die-and-our-son-was-not-a-drug-addict/
[dc] => Array
(
[creator] => Sally Scully
)
[pubdate] => Mon, 31 Oct 2022 07:06:52 +0000
[category] => ShowsaddictdieDomenicaDrugFrancoGattisonStefaniaWife
[guid] => https://coolnspicy.com/?p=55826
[description] =>
The episode of Sunday In today, 30 October 2022, opens with the memory of Franco Gatti. Guest of Mara Venier there is Stefania Picasso, the wife of the singer of Ricchi e Poveri, who passed away on 18 October last. The presenter, a very good friend of Franco Gatti and his ... Read more
[content] => Array
(
[encoded] =>
The episode of Sunday In today, 30 October 2022, opens with the memory of Franco Gatti. Guest of Mara Venier there is Stefania Picasso, the wife of the singer of Ricchi e Poveri, who passed away on 18 October last. The presenter, a very good friend of Franco Gatti and his family, decided to pay homage to him with a moving memory, also through the words of his beloved Stefania.
Dancing, clash between Dario Cassini and Selvaggia Lucarelli. Carolyn Smith bursts in: “Unacceptable!”
Franco Gatti, his wife Stefania on Domenica In
«We met through Angela Brambati, I was a young girl and as soon as I saw him, it was love at first sight. I went to my sister and told her: “I’m going to marry this one”. And she: “Are you stupid?”. Our first date was not exactly romantic, because we went to the cinema, but to see Alien “- says Stefania, Franco Gatti’s wife -” Seven years after our first meeting we got married, at first it was not easy because I was jealous. But I couldn’t be at the side of an artist with that jealousy, he always toured Italy and I couldn’t continue like this ».
Franco Gatti, his wife Stefania: “It’s not true that he let himself die”
Stefania, Franco Gatti’s wife, denies that the singer let himself die from the pain caused by the death of their son Alessio, who died of an overdose at the age of 23: «It’s not true. Franco had been suffering from previous diseases for some time and two years ago he was infected with Covid. Since then, his condition has progressively worsened. And that is why, after the reunion in Sanremo, he had decided not to go on tour with the Ricchi e Poveri: he could not keep up with those rhythms in his conditions ». And on the pain of her son’s death, Stefania explains: «It is something that tears the heart and any parent would give their life for that of their child, but unfortunately this was useless. Franco, like me, tried in every way to transform his pain. In unsuspecting times, before Alessio’s death, I was already following specific paths and dealing with topics such as life after death. It was a way to give hope to those parents who could not bear such a heavy bereavement. Franco had understood all this and gave me the best gift: accompanying me to one of my conferences, even going up on stage ».
Franco Gatti, his wife Stefania: “Alessio was not a drug addict”
Then there was talk of the death of Alessio, the youngest son of Franco Gatti and Stefania Picasso. «I have never been lacking for anything in terms of pain, my sister left this dimension when she was 30 years old. And a few weeks earlier I had received a message from my sister, who announced the tragedy, but I hadn’t given it any weight “- explains Franco Gatti’s wife -” My son Alessio was not a drug addict, at 22 he started to be a stock trader. That evening I asked him to come with us to Sanremo, but he refused because he had to finish a platform. A friend of his confirmed to me that Alessio had found a substance that would have made him stay up all night to finish that job. He probably mixed it with something, but above all, not being a drug addict, he didn’t know how to dose it ». After the death of his son Alessio, Franco Gatti told the program Come to me: «My son drank a lot and it was also his misfortune. He fucked up, taking drugs the first and last time of his life, at a time when he wasn’t well. And he paid for it like that. ” His wife Stefania commented on her husband’s words: «Yes, my son and his friends used to have big drinks. But they were very responsible and, in turn, there was always someone who stayed sober to drive. When I asked Franco why he had made those statements, his answer was: “Because I want to help other boys” ».
)
[summary] =>
The episode of Sunday In today, 30 October 2022, opens with the memory of Franco Gatti. Guest of Mara Venier there is Stefania Picasso, the wife of the singer of Ricchi e Poveri, who passed away on 18 October last. The presenter, a very good friend of Franco Gatti and his ... Read more
[atom_content] =>
The episode of Sunday In today, 30 October 2022, opens with the memory of Franco Gatti. Guest of Mara Venier there is Stefania Picasso, the wife of the singer of Ricchi e Poveri, who passed away on 18 October last. The presenter, a very good friend of Franco Gatti and his family, decided to pay homage to him with a moving memory, also through the words of his beloved Stefania.
Dancing, clash between Dario Cassini and Selvaggia Lucarelli. Carolyn Smith bursts in: “Unacceptable!”
Franco Gatti, his wife Stefania on Domenica In
«We met through Angela Brambati, I was a young girl and as soon as I saw him, it was love at first sight. I went to my sister and told her: “I’m going to marry this one”. And she: “Are you stupid?”. Our first date was not exactly romantic, because we went to the cinema, but to see Alien “- says Stefania, Franco Gatti’s wife -” Seven years after our first meeting we got married, at first it was not easy because I was jealous. But I couldn’t be at the side of an artist with that jealousy, he always toured Italy and I couldn’t continue like this ».
Franco Gatti, his wife Stefania: “It’s not true that he let himself die”
Stefania, Franco Gatti’s wife, denies that the singer let himself die from the pain caused by the death of their son Alessio, who died of an overdose at the age of 23: «It’s not true. Franco had been suffering from previous diseases for some time and two years ago he was infected with Covid. Since then, his condition has progressively worsened. And that is why, after the reunion in Sanremo, he had decided not to go on tour with the Ricchi e Poveri: he could not keep up with those rhythms in his conditions ». And on the pain of her son’s death, Stefania explains: «It is something that tears the heart and any parent would give their life for that of their child, but unfortunately this was useless. Franco, like me, tried in every way to transform his pain. In unsuspecting times, before Alessio’s death, I was already following specific paths and dealing with topics such as life after death. It was a way to give hope to those parents who could not bear such a heavy bereavement. Franco had understood all this and gave me the best gift: accompanying me to one of my conferences, even going up on stage ».
Franco Gatti, his wife Stefania: “Alessio was not a drug addict”
Then there was talk of the death of Alessio, the youngest son of Franco Gatti and Stefania Picasso. «I have never been lacking for anything in terms of pain, my sister left this dimension when she was 30 years old. And a few weeks earlier I had received a message from my sister, who announced the tragedy, but I hadn’t given it any weight “- explains Franco Gatti’s wife -” My son Alessio was not a drug addict, at 22 he started to be a stock trader. That evening I asked him to come with us to Sanremo, but he refused because he had to finish a platform. A friend of his confirmed to me that Alessio had found a substance that would have made him stay up all night to finish that job. He probably mixed it with something, but above all, not being a drug addict, he didn’t know how to dose it ». After the death of his son Alessio, Franco Gatti told the program Come to me: «My son drank a lot and it was also his misfortune. He fucked up, taking drugs the first and last time of his life, at a time when he wasn’t well. And he paid for it like that. ” His wife Stefania commented on her husband’s words: «Yes, my son and his friends used to have big drinks. But they were very responsible and, in turn, there was always someone who stayed sober to drive. When I asked Franco why he had made those statements, his answer was: “Because I want to help other boys” ».
